Gheorghe Cantacuzino may refer to several members of the Cantacuzino family:
Gheorghe Grigore Cantacuzino (1833–1913), twice prime minister of Romania Grigore Gheorghe Cantacuzino (1872–1930), mayor of Bucharest Gheorghe Cantacuzino-Grănicerul, soldier and fascist politician Gheorghe I. Cantacuzino (born 1937), historian George Matei Cantacuzino (1899–1960), Romanian architect, painter and essayist