Luke Jackson may refer to:
Arts and entertainment Luke Jackson (singer), British singer Luke Jackson, the title character of Cool Hand Luke, portrayed by Paul Newman Luke Jackson, author of Freaks, Geeks, and Asperger Syndrome
Sports Luke Jackson (baseball), (born 1991), American baseball player Luke Jackson (basketball, born 1981), American basketball player in the 2000s Lucious Jackson (1941–2022), also known as Luke Jackson, American basketball player in the 1960s and 1970s Luke Jackson (boxer) (born 1985), Australian amateur boxer Luke Jackson (footballer) (born 2001), Australian rules footballer