Francke is a German surname. Notable people with the surname include:
August Hermann Francke (1663–1727), German Protestant theologian Arne Francke (1904–1973), Swedish horse rider Donald E. Francke (1910–1978), American pharmacist, editor and author Gloria Niemeyer Francke (1922–2008), American pharmacist and science writer Klaus Francke (1936–2020), German politician Kuno Francke (1855–1930), educator and historian Malcolm Francke (born 1939), Australian cricketer Master Francke (c.1380–1440), German painter Michael Francke (1946–1989), Director of the Oregon Department of Corrections Paul Francke (architect) (c.1537–1615), German architect and master builder Paul Francke (footballer) (died in World War I), German football player and founder member of Bayern Munich Paul Francke (geologist) (1897–1957), German geologist Paul Francke (musician) (born 1979), American musician Rend al-Rahim Francke (born 1949), Iraqi political activist and ambassador to the United States Rudolf Francke, German First World War flying ace Stewart Francke (1958–2025), American singer-songwriter
See also Franke Francken Franck (disambiguation)