William Spicer may refer to:
William Spicer (14th-century MP), MP for Devizes William A. Spicer (1865–1952), Seventh-day Adventist minister and president of the General Conference of Seventh-day Adventists William C. Spicer (1868–?), American college football player and coach William E. Spicer (1929–2004), American engineering academic William L. Spicer (1918–1991), American businessman and state chairman of the Arkansas Republican Party William Spicer (cricketer) (1846–1892), English cricketer William Spicer (Medal of Honor) (1864–1949), gunner's mate in the United States Navy who received the Medal of Honor William Spicer (MP for Exeter) (c. 1735–1788), British MP for Exeter, 1767–1768