Frederick Bruce may refer to:
F. F. Bruce (Frederick Fyvie Bruce, 1910–1990), Scottish Biblical scholar Frederick Bruce (diplomat) (1814–1867), British diplomat Frederick Malloch Bruce (1912–1997), Scottish electrical engineer and educationalist
See also Frederick Nanka-Bruce (1878–1953), physician, journalist and politician in the Gold Coast Frederick Bruce-Lyle (1953–2016), Ghanaian-born judge who served in the Caribbean