Simsim was a 14th-century state located in the historical territories of modern-day Chechnya and Ingushetia.

Simsim may also refer to:

Places The Simsim Caves in the Tarim Basin Simsim, Gaza, a Palestinian Arab village depopulated in 1948 in what is today Israel

Entertainment Alam Simsim, the Egyptian version of the children's television series Sesame Street Iftah Ya Simsim, the Kuwaiti version of Sesame Street Shara'a Simsim, the Palestinian version of Sesame Street

Other Simsim, the word for sesame in various Semitic languages; also widely used in Arab-influenced East Africa