The Pythia is an ancient Greek priestess at the Oracle of Apollo at Delphi.

Pythia may also refer to: Pythia (drag queen)

In science 432 Pythia, a main belt asteroid named after the Greek priestess PYTHIA, a particle physics event generator Pythia (gastropod), a genus of gastropods in the family Ellobiidae Pythia (machine learning), an ancient text restoration deep neural network model.

In fiction Pythia (Battlestar Galactica), a fictional character from the new Battlestar Galactica Pythia of Gallifrey, a fictional character from the British TV series Doctor Who

In music Pythia (band), a British symphonic metal band

See also Pythia Island, Antarctica