Sextus Pomponius () was a Roman jurist who lived during the reigns of Hadrian, Antoninus Pius, and Marcus Aurelius.
Name Sextus was a fairly common Roman given name () while his surname seems to indicate he belonged to the Pomponia family (). Other writers have expressed a view that the name Sextus Pomponius was shared by another jurist, although Puchta suggested the assumption of two Pomponii was unsupported by the evidence.Cursus der Institution, vol. i. p. 444.
Works S. Pomponius wrote a book on the law up to the time of Hadrian, known as the Enchiridion (, Enkheidírion, "Handbook"). A long excerpt of the work forms part of Justinian's Digest dealing with the origin of the Roman Constitution and various offices.
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