NBC 16 may refer to one of the following television stations in the United States:
Current KMTR, Eugene, Oregon KSNF, Joplin, Missouri WNDU-TV, South Bend, Indiana WPBI-LD2, Lafayette, Indiana WWPI-LD, Fort Kent / Presque Isle, Maine
Former KEDD-TV, Wichita, Kansas KTGF (now KJJC-TV), Great Falls, Montana K16BY (now KIVY-LD), Crockett, Texas Was a translator for KETK-TV in Jacksonville / Tyler, Texas