Compton House may refer to:

In England Compton House, a mansion in Over Compton, Dorset Compton Beauchamp House, a mansion in Oxfordshire Compton House, in Wentworth, Virginia Water, Surrey - where Prajadhipok, King of Siam lived, and died in 1941 Compton Wynyates, a Tudor country house in Warwickshire Compton Verney House, a mansion in Warwickshire Compton Park House, Compton Chamberlayne or Compton House, a country house in Wiltshire Compton House, Liverpool, a department store built in 1867

In the United States The Arthur H. Compton House, Chicago, Illinois The David Compton House, Mauricetown, New Jersey The Captain Edward Compton House, Mauricetown, New Jersey The Compton-Wood House, Little Rock, Arkansas