MHSS may refer to:

Malayan High School of Science, a private secondary educational institution in Manila, Philippines Manakamana Higher Secondary School, a secondary school in Jorpati, Kathmandu, Nepal Mezhür Higher Secondary School, a private school in Kohima, Nagaland, India Monk's Hill Secondary School, a defunct secondary school in Newton, Singapore

See also Minister of Health and Social Services (disambiguation)