Masters of the Universe is a media franchise based on a line of toys produced during the 1980s by Mattel.

Masters of the Universe may also refer to:

Mattel franchise Films and TV series He-Man and the Masters of the Universe, an animated TV series produced from 1983 to 1985 The New Adventures of He-Man, an early-1990s animated TV series based on He-Man and the Masters of the Universe characters He-Man and the Masters of the Universe (2002 TV series), a reboot of the 1983 animated series He-Man and the Masters of the Universe Masters of the Universe (1987 film), a live action feature film starring Dolph Lundgren and Frank Langella Masters of the Universe (TV series) (2021–2024), a revival, in 3-parts, of the 1983 animated series He-Man and the Masters of the Universe He-Man and the Masters of the Universe (2021 TV series), a remake of the 1983 animated series He-Man and the Masters of the Universe Masters of the Universe (2026 film), an American superhero film

Video games Masters of the Universe: The Power of He-Man, a 1983 game designed by Intellivision Masters of the Universe: The Super Adventure, an interactive fiction game released in 1987 by U.S. Gold Masters of the Universe: The Arcade Game, an arcade-style computer game released in 1987 by U.S. Gold Masters of the Universe: The Movie, 1987, (based on the Masters of the Universe film) from Gremlin Graphics

Other Masters of the Universe (comics), the various comics series He-Man and the Masters of the Universe (2012 DC comic) The Masters of the Universe Role Playing Game, a 1985 role-playing game based on the Mattel franchise

Music Masters of the Universe (Binary Star album), 2000 Masters of the Universe (Hawkwind album), 1977 Masters of the Universe (Pulp album), 1994 "Masters of the Universe" (song), 2000, by Juno Reactor

Other uses Masters of the Universe? NATO's Balkan Crusade, a 2000 book edited by Tariq Ali Masters of the Universe (book), 2012, on the topic of neoliberalism Masters of the Universe (MOTU), maintainers of the community-supported components of the Ubuntu operating system

See also "Master of the Universe", high-flyers on Wall Street, a usage found in the Tom Wolfe novel The Bonfire of the Vanities and its film adaptation Master of The Universe (disambiguation) He-Man (disambiguation)