Afrin may refer to:

Places Afrin Canton, one of the cantons of the de facto autonomous Democratic Federation of Northern Syria Afrin District, a district of Aleppo Governorate in northern Syria. The administrative centre is the city of Afrin Afrin Subdistrict, a subdistrict of the Afrin District Afrin Region, the westernmost of the three regions of the de facto autonomous Democratic Federation of Northern Syria Afrin River, a river in Turkey and Syria Afrin Dam, dam on the Afrin River in northwest Syria Afrin, Syria, a city in northwestern Syria, administratively part of Aleppo Governorate

Institutions Afrin SC, a football club based in Afrin, Syria University of Afrin, an unrecognized university established in the city of Afrin by the Afrin Canton Board of Education

Products Oxymetazoline, sold under the brand name Afrin in the United States, is an over-the-counter nasal spray medication to treat congestion

People Given name Afrin Ali (born 1986), Indian politician Surname Jill Afrin (born 1962), psychiatrist Nahid Afrin (born 2001), Indian playback singer Narin Afrin (born c. 1974), militant