St. Charles School or Saint Charles School or variations may refer to:
in Canada St. Charles Elementary School, formerly or also known as École St-Charles School, in Pierrefonds-Roxboro, Montreal, Quebec, a school in the Lester B. Pearson School Board's district
in the United States St. Charles School (San Francisco), California, one of San Francisco's Designated Landmarks Saint Charles Preparatory School, Columbus, Ohio
See also St. Charles College Historic District, Catonsville, Maryland, listed on the National Register of Historic Places