Mary Watson may refer to:
Mary Watson (chemist) (1856–1933), British chemist Mary Watson (pioneer) (1860–1881), Australian folk heroine Mary Watson (author) (fl. 2000s), South African author Mrs Watson (Mary Morstan), Mary, wife of Dr Watson, Sherlock Holmes character Mary Jane Watson, Spider-Man character Mary Jo Watson, Seminole art historian Mary Spencer Watson (1913–2006), English sculptor
See also Mary Watson Weaver (1903–1990), American composer, pianist, and poet Mary Watson-Wentworth, Marchioness of Rockingham (1735–1804), English wife of Charles Watson-Wentworth, 2nd Marquess of Rockingham Mary Watson Whitney (1847–1921), American astronomer Mary Gordon-Watson (born 1948), British equestrian Mary DeCongé-Watson (1933–2025), American mathematician and former religious sister