RPI may refer to:
Universities Rensselaer Polytechnic Institute, Troy, New York, US Richmond Professional Institute, merged into Virginia Commonwealth University
Science and technology Raspberry Pi (RPi), single-board computers and microcontrollers by public traded Raspberry Pi Ltd. Reticulocyte production index, a blood test result Ribose-5-phosphate isomerase (Rpi), an enzyme
Organizations Recognition Professionals International Republican Party of India Republican Party of Iowa
Other Rating percentage index, in college sports Retail price index, UK inflation measure Revenue Protection Inspector, on UK public transport Rock progressivo italiano, Italian progressive rock
See also RP 1 (disambiguation) RPL (disambiguation)