Isobel is the Scottish variant of Isabel, a feminine given name.

Isobel may also refer to:

Music "Isobel" (song), by Björk from the album Post "Isobel", by Dido from her album No Angel

Film and television Isobel (film), also known as The Trail's End, a 1920 film directed by Edwin Carewe, from the novel by James Oliver Curwood "Isobel" (The Vampire Diaries), an episode of the TV series The Vampire Diaries

Other uses Isobel, a contour line in mapping of environmental noise, connecting points of equal sound pressure Isobel (HBC vessel), operated by the HBC from 1850 to 1857, see Hudson's Bay Company vessels Isobel: A Romance of the Northern Trail, 1913 novel by James Oliver Curwood See also Isabel (disambiguation) Cyclone Isobel (disambiguation), four cyclones in the southern hemisphere