HSP may refer to:

Biology, chemistry, and medicine Hansen solubility parameters Heat shock protein Henoch–Schönlein purpura Hereditary spastic paraplegia Highly sensitive person, with high sensory processing sensitivity (SPS)

Mathematics, software, and technology Hidden subgroup problem, in mathematics High Speed Photometer, Hubble Space Telescope instrument Host signal processing, software emulating hardware Hot Soup Processor, a programming language High-Scoring Segment Pair, in the BLAST algorithm Headset Profile, a Bluetooth profile

Education Harvard Sussex Program, an inter-university collaboration Holy Spirit Preparatory School, in Atlanta, Georgia, United States

Political parties Croatian Party of Rights (Croatian: ) People's Voice Party (Turkish: ), Turkey

Other uses Halal snack pack, an Australian dish