Amphiphysin

Amphiphysin is a protein that in humans is encoded by the AMPH gene.

Function This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff person syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined.

Interactions Amphiphysin has been shown to interact with DNM1, Phospholipase D1, CDK5R1, PLD2, CABIN1 and SH3GL2.

See also

References

Further reading

Review.

External links Bringing your curves to the bar, amphiphysin home page