Echenique is a surname of Basque origin. Echenique, (spelled Etxenike in standard Basque means "close to the house". Other spelling variants are Echeñique and Etchenique. Notable people with the surname include:
Sport Karla Echenique, Dominican volleyball player José Echenique, Venezuelan basketball player Rafael Echenique, Argentine golfer
Music Cecilia Echenique, Chilean singer-songwriter Benjamín Juárez Echenique, Mexican popular musical conductor José Miguel "Negro" Piñera Echenique, Chilean musician
Politics Gertrudis Echenique, Chilean First Lady between 1896 and 1901. Wife of Federico Errázuriz Echaurren José Rufino Echenique, Peruvian politician. President of Peru from 1851 until 1855 Pablo Echenique Robba, Spanish scientist and politician Sebastián Piñera Echenique, Chilean politician, member of the National Renewal (RN) José Piñera Echenique, Chilean economist
Science Pedro Miguel Echenique, Spanish theoretical physicist and from 1980 to 1984 minister of education in the Basque Country
Literature Alfredo Bryce Echenique, a Peruvian writer