Wayne County Courthouse may refer to:
Wayne County Courthouse (Georgia), Jesup, Georgia, listed on the National Register of Historic Places (NRHP) Wayne County Courthouse (Illinois), in Fairfield, Illinois, built in 1890s Wayne County Courthouse (Indiana), in Richmond, Indiana, 1893-built, NRHP-listed Wayne County Courthouse (Iowa), in Corydon, Iowa Wayne County Building, Detroit, Michigan, formerly known as Wayne County Courthouse, NRHP-listed Wayne County Courthouse (Nebraska), in Wayne, Nebraska, 1899-built and NRHP-listed Wayne County Courthouse District, in Wooster, Ohio, 1879-built and NRHP-listed Wayne County Courthouse (Tennessee), Waynesboro, Tennessee, NRHP-listed