Mendieta is a Basque and Spanish surname. Notable people with the surname include:
Ana Mendieta (1948–1985), Cuban-American artist Ascención Mendieta (1925–2019), Spanish activist Carlos Mendieta (1873–1960), Cuban politician Gaizka Mendieta (born 1974), Spanish footballer Gerónimo de Mendieta (1525–1604), Franciscan missionary and historian Junior Mendieta (born 1993), Argentine footballer Víctor René Mendieta Jr. (born 1982), footballer William Mendieta (born 1989), Paraguayan footballer