Depletion may refer to:
Environment Resource depletion, decline of resources Gas depletion, decline of oil supply Nutrient depletion, loss of nutrients in a habitat Oil depletion, decline of oil supply Overdrafting, extracting groundwater beyond the equilibrium yield of an aquifer Ozone depletion, a decline in the total amount of ozone in Earth's atmosphere
Physics Depletion force, an effective force in molecular and colloidal systems Depletion region, in semiconductor physics Grain boundary depletion, a mechanism of corrosion
Other uses Depleted uranium Ego depletion, idea that self-control or willpower draws upon a limited pool of mental resources that can be used up Depletion (accounting), an accounting and tax concept used in mining, timber, petroleum, or other similar industries T-cell depletion, process of T cell removal or reduction