Pickrell is a surname. Notable people with the surname include:
E. R. Pickrell (1858–1894), American politician Ray Pickrell (1938–2006), English short-circuit motorcycle road racer Riley Pickrell (born 2001), Canadian cyclist Robert Pickrell (1922–2017), American politician Tony Pickrell (1942–2015), Welsh footballer
See also Picknell, surname Pickrel, surname Pickrell, Nebraska Tamsin Pickeral (born 1971), art historian