Strube is a surname. Notable people with the surname include:
Cordelia Strube, Canadian playwright and novelist Gardiner A. Strube, American drummer Gustav Strube (1867–1953), German conductor and composer Henrik Strube (born 1949), Danish musician Jan Strube, Dutch painter Jürgen F. Strube (born 1939), German businessman Sidney Strube (1891–1956), British cartoonist