Southpaw, a colloquial term for a left-handed individual, particularly in sports, may also refer to:
Arts and entertainment Film Southpaw (film), a 2015 film starring Jake Gyllenhaal Southpaw: The Francis Barrett Story, a 1999 documentary film about boxer Francie Barrett
Literature Southpaw (comics), a fictional character in the Marvel comic She-Hulk The Southpaw, a 1953 novel by Mark Harris
Music Southpaw (album), by Gilbert O'Sullivan, 1977 Southpaw: Original Motion Picture Soundtrack, an album by James Horner, 2015 Southpaw: Music from and Inspired by the Motion Picture, an album by various artists, 2015 "Southpaw" (Pink Lady song), 1978 "Southpaw", a song by the Afghan Whigs from Up in It, 1990 "Southpaw", a song by Morrissey from Southpaw Grammar, 1995
Sports Southpaw stance, the normal stance for a left-handed boxer Southpaw (Chicago White Sox mascot)
Other uses Southpaw Technology, an open-source software company Southpaw Entertainment, a film and television production company founded by Richard B. Lewis Southpaw, a NODAL-related gene involved in left-right body patterning in vertebrates