S100 or S-100 may refer to:
Aviation Colyaer Freedom S100, a Spanish amphibious ultralight aircraft Colyaer Gannet S100, a Spanish ultralight flying boat Colyaer Martin3 S100 is a Spanish ultralight aircraft Schiebel Camcopter S-100, an unmanned aerial vehicle
Consumer electronics Canon PowerShot S100, a digital camera Guild S-100, an electric guitar Lenovo IdeaPad S100, a netbook computer Qtek S100, a mobile phone
Trains AVE Class 100, or S100, a high speed train USATC S100 Class, a 1942 steam locomotive class
Other S-100 bus, an early computer bus S-100, an International Hydrographic Organization standard S100 protein, low-molecular-weight proteins in vertebrates The road number used in the Netherlands for inner-city ring roads A class of WWII German E-Boat. Škoda 100, a 1970s car
See also