Charles Thornton may refer to:

Tex Thornton (1913–1981), American businessman Charles Thornton (cricketer) (1850–1929), English cricketer Charles "Cookie" Thornton, resident of Kirkwood, Missouri involved, in Kirkwood City Council shooting Charles Irving Thornton (1841–1842), American infant from the state of Virginia Charles Jonas Thornton (1850–1932), political figure in Durham, Ontario Charles Wade Thornton (1764–1854), British military officer Charles E. Thornton (1930s–1985), medical reporter and the first American journalist killed in Afghanistan after the Soviet invasion of 1979