Carboxy-lyases, also known as decarboxylases, are carbon–carbon lyases that add or remove a carboxyl group from organic compounds. These enzymes catalyze the decarboxylation of amino acids and alpha-keto acids.
Classification and nomenclature Carboxy-lyases are categorized under EC number 4.1.1. Usually, they are named after the substrate whose decarboxylation they catalyze, for example pyruvate decarboxylase catalyzes the decarboxylation of pyruvate.
Examples Aromatic-L-amino-acid decarboxylase Glutamate decarboxylase Histidine decarboxylase Ornithine decarboxylase Phosphoenolpyruvate carboxylase Pyruvate decarboxylase RuBisCO – the only carboxylase that leads to a net fixation of carbon dioxide Uridine monophosphate synthetase Uroporphyrinogen III decarboxylase enoyl-CoA carboxylases/reductases (ECRs)
See also Enzymes Lyases List of EC numbers of enzymes belonging to category EC 4.1
References
External links