RSX may refer to:
Computing RSX, a RISC CPU from Encore Computer RSX-11, an operating system family developed by Digital Equipment Corporation RSX 'Reality Synthesizer', a graphics chip for the PS3 Resident System Extension, part of the CP/M Plus operating system
Other uses Acura RSX, an automobile manufactured by Honda Motor Co. Rhein-Sieg-Express, a German regional train service RS:X (sailboard) RSX Energy, a Canadian oil and gas company Label for an X-ray observation made by ROSAT