Panola may refer to several places in the United States:
Panola, Crenshaw County, Alabama, an unincorporated community Panola, Sumter County, Alabama, a census-designated place Panola County, Mississippi Panola County, Texas Panola, Illinois, a village Panola, Michigan, an unincorporated community Panola, Oklahoma, a census-designated place Panola, Texas, an unincorporated community