Pleasant Run may refer to the following places in the United States:
Pleasant Run, Ohio, a census-designated place in Hamilton County Pleasant Run Elementary School, a public school in Lancaster, Texas Pleasant Run Township, Lawrence County, Indiana Pleasant Run Village, a former village in Readington Township, New Jersey Pleasant Run (New Jersey), a brook in central New Jersey Pleasant Run, West Virginia Pleasant Run Greenway, a recreational trail in Indianapolis, Indiana
Other uses Pleasant Run (painting), a painting by T. C. Steele